2021Journal of Oral and Maxillofacial PathologyOpen access

Keratinizing pleomorphic adenoma

S. Sankari, Prakash Dhanavelu, P. Sangeetha Priya, Sudha Jimson

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Abstract

Pleomorphic adenoma is the most common benign salivary gland tumour characterized by great histologic diversity. The presence of extensive squamous metaplasia and numerous keratin pearls is mostly uncommon in the microscopic study and can signify a potential pitfall in the histopathological diagnosis Pleomorphic adenoma can show the presence of squamous metaplasia with keratin pearls as a rare finding and is encountered most often in the parotid gland (84%) and 6% in the minor salivary gland. Here we present a case report of a rare histopathological variant of pleomorphic adenoma with exuberant squamous metaplasia and keratin pearl formation of the minor salivary gland in an unusual location.

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Pleomorphic adenoma is the most common benign salivary gland tumour characterized by great histologic diversity. The presence of extensive squamous metaplasia and numerous keratin pearls is mostly uncommon in the microscopic study and can signify a potential pitfall in the histopathological diagnosis Pleomorphic adenoma can show the presence of squamous metaplasia with keratin pearls as a rare finding and is encountered most often in the parotid gland (84%) and 6% in the minor salivary gland. Here we present a case report of a rare histopathological variant of pleomorphic adenoma with exuberant squamous metaplasia and keratin pearl formation of the minor salivary gland in an unusual location.

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Available abstract

Pleomorphic adenoma is the most common benign salivary gland tumour characterized by great histologic diversity. The presence of extensive squamous metaplasia and numerous keratin pearls is mostly uncommon in the microscopic study and can signify a potential pitfall in the histopathological diagnosis Pleomorphic adenoma can show the presence of squamous metaplasia with keratin pearls as a rare finding and is encountered most often in the parotid gland (84%) and 6% in the minor salivary gland. Here we present a case report of a rare histopathological variant of pleomorphic adenoma with exuberant squamous metaplasia and keratin pearl formation of the minor salivary gland in an unusual location.

Key concepts: Pleomorphic adenoma, Squamous metaplasia, Keratin, Pathology, Salivary gland, Metaplasia, Parotid gland, Mixed tumor

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