Decision letter: Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses
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Abstract
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Abstract
At mammalian synapses the clathrin adaptor AP-2 plays a crucial role in the endocytic retrieval of a subset of synaptic vesicle proteins from the presynaptic cell surface, while clathrin is dispensable.
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At mammalian synapses the clathrin adaptor AP-2 plays a crucial role in the endocytic retrieval of a subset of synaptic vesicle proteins from the presynaptic cell surface, while clathrin is dispensable.
Key concepts: Endocytic cycle, Clathrin, Clathrin adaptor proteins, Endocytosis, Synaptic vesicle, Synaptic vesicle recycling, Signal transducing adaptor protein, Cell biology