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2014•Bukovinian Medical HeraldOpen access

Growth-differentiation factor 15, N-terminal pro-brain natriuretic peptide, structural and functional changes of the heart in patients with heart failure and normal ejection fraction after myocardial infarction on the background of arterial hypertension

В. Д. Сыволап, Ya. V. Zemlianyi

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Abstract

Levels of GDF-15, NTproBNP, structural and functional changes of the heart were assessed in 69 patients with postinfarction cardiosclerosis and preserved left ventricular ejection fraction (EF>45 %). We found out that patients with heart failure and preserved ejection fraction after myocardial infarction on the background of arterial hypertension have increased levels of GDF 15 and NTproBNP. These biomarkers were correlated with left ventricular diastolic dysfunction and left atrial volume index.

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Levels of GDF-15, NTproBNP, structural and functional changes of the heart were assessed in 69 patients with postinfarction cardiosclerosis and preserved left ventricular ejection fraction (EF>45 %). We found out that patients with heart failure and preserved ejection fraction after myocardial infarction on the background of arterial hypertension have increased levels of GDF 15 and NTproBNP. These biomarkers were correlated with left ventricular diastolic dysfunction and left atrial volume index.

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Available abstract

Levels of GDF-15, NTproBNP, structural and functional changes of the heart were assessed in 69 patients with postinfarction cardiosclerosis and preserved left ventricular ejection fraction (EF>45 %). We found out that patients with heart failure and preserved ejection fraction after myocardial infarction on the background of arterial hypertension have increased levels of GDF 15 and NTproBNP. These biomarkers were correlated with left ventricular diastolic dysfunction and left atrial volume index.

Key concepts: Ejection fraction, Cardiology, Internal medicine, Heart failure, Myocardial infarction, Medicine, Diastole, Stroke volume

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Growth-differentiation factor 15, N-terminal pro-brain natriuretic peptide, structural and functional changes of the heart in patients with heart failure and normal ejection fraction after myocardial infarction on the background of arterial hypertension — Research Paper | ScholarLens