2021MathematicsOpen access

An SIRS Epidemic Model Supervised by a Control System for Vaccination and Treatment Actions Which Involve First-Order Dynamics and Vaccination of Newborns

S. Alonso‐Quesada, Manuel De la Sen, Raúl Nistal

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Abstract

This paper analyses an SIRS epidemic model with the vaccination of susceptible individuals and treatment of infectious ones. Both actions are governed by a designed control system whose inputs are the subpopulations of the epidemic model. In addition, the vaccination of a proportion of newborns is considered. The control reproduction number Rc of the controlled epidemic model is calculated, and its influence in the existence and stability of equilibrium points is studied. If such a number is smaller than a threshold value R¯c, then the model has a unique equilibrium point: the so-called disease-free equilibrium point at which there are not infectious individuals. Furthermore, such an equilibrium point is locally and globally asymptotically stable. On the contrary, if Rc>R¯c, then the model has two equilibrium points: the referred disease-free one, which is unstable, and an endemic one at which there are infectious individuals. The proposed control strategy provides several free-design parameters that influence both values Rc and R¯c. Then, such parameters can be appropriately adjusted for guaranteeing the non-existence of the endemic equilibrium point and, in this way, eradicating the persistence of the infectious disease.

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What this paper is about

This paper analyses an SIRS epidemic model with the vaccination of susceptible individuals and treatment of infectious ones. Both actions are governed by a designed control system whose inputs are the subpopulations of the epidemic model. In addition, the vaccination of a proportion of newborns is considered. The control reproduction number Rc of the controlled epidemic model is calculated, and its influence in the existence and stability of equilibrium points is studied. If such a number is smaller than a threshold value R¯c, then the model has a unique equilibrium point: the so-called disease-free equilibrium point at which there are not infectious individuals. Furthermore, such an equilibrium point is locally and globally asymptotically stable. On the contrary, if Rc>R¯c, then the model has two equilibrium points: the referred disease-free one, which is unstable, and an endemic one at which there are infectious individuals. The proposed control strategy provides several free-design parameters that influence both values Rc and R¯c. Then, such parameters can be appropriately adjusted for guaranteeing the non-existence of the endemic equilibrium point and, in this way, eradicating the persistence of the infectious disease.

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Available abstract

This paper analyses an SIRS epidemic model with the vaccination of susceptible individuals and treatment of infectious ones. Both actions are governed by a designed control system whose inputs are the subpopulations of the epidemic model. In addition, the vaccination of a proportion of newborns is considered. The control reproduction number Rc of the controlled epidemic model is calculated, and its influence in the existence and stability of equilibrium points is studied. If such a number is smaller than a threshold value R¯c, then the model has a unique equilibrium point: the so-called disease-free equilibrium point at which there are not infectious individuals. Furthermore, such an equilibrium point is locally and globally asymptotically stable. On the contrary, if Rc>R¯c, then the model has two equilibrium points: the referred disease-free one, which is unstable, and an endemic one at which there are infectious individuals. The proposed control strategy provides several free-design parameters that influence both values Rc and R¯c. Then, such parameters can be appropriately adjusted for guaranteeing the non-existence of the endemic equilibrium point and, in this way, eradicating the persistence of the infectious disease.

Key concepts: Equilibrium point, Epidemic model, Basic reproduction number, Vaccination, Infectious disease (medical specialty), Mathematics, Stability theory, Applied mathematics

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