2015•PubMedRequires access

[Current concepts regarding cortical dementia].

Shun Shimohama

Abstract

Dementia manifests during the presenile and senile periods in many diseases and pathological conditions. Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) are the two main diseases in which cortical dementia is observed. FTLD includes frontotemporal dementia (FTD), progressive non-fluent aphasia (PNFA), and semantic dementia (SD). Cortical dementia has also been described in posterior cortical atrophy (CPA) and primary progressive non-fluent or logopenic aphasia (PNFLA). This article describes and discusses historical changes in the disease concept; diagnostic characteristics, including pathology and imaging analysis; clinical symptoms based on local cognitive function in the cerebral cortex; and other recent topics on dementia.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Semantic dementia, Primary progressive aphasia, Frontotemporal dementia, Dementia, Aphasia, Posterior cortical atrophy, Frontotemporal lobar degeneration, Neuroscience