2010•PubMedOpen access

Examination of formulation and process factors on the characteristics of fast dissolving and fast disintegrating tablets manufactured by a direct compression process.

Bartelt, Luther, Lakshmanane, Prem, Baric, Ralph, Desilva, Aravinda, David, Margolis

Abstract

In this study, in a high-risk population of patients admitted for COVID-19, we found an earlier time to hospital discharge among participants receiving CCP with nAb titers of >1:640 compared with participants receiving CCP with a lower nAb titer and no CCP-related AEs. The significance of our research is in identifying a dose response of CCP and clinical outcomes based on nAb titer. Although limited by a small study size, these findings support further study of high-nAb-titer CCP defined as >1:640 in the treatment of COVID-19.

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Available abstract

Key concepts: Process (computing), Process engineering, Compression (physics), Manufacturing engineering, Materials science, Computer science, Engineering drawing, Engineering