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[Phospholipid characteristics of the HDLP2 and HDLP3 composition in dysalphalipoproteinemia].

E N Gerasimova, T M Pham, S N Suchkova, N V Chepurnenko, Polesskiĭ Va

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Abstract

There has been determined the phospholipid composition in HDLP2 and HDLP3 obtained from the blood plasma of males with different cholesterol (CS) level of HDLP. An increase in CS of HDLP is shown to be associated with the increase in a percentage of phosphatidylcholine, a proportion of phosphatidylcholine/sphingomyelin and a reduction of the percentage of sphingomyelin (mainly in HDLP2) and to a lesser extent--in HDLP3. A direct correlation has been established between the level of CS of HDLP obtained from the blood plasma of males living in 3 different geographical zones of the USSR and the indices of the phospholipid composition of HDLP2. Changes found in the phospholipid composition of HDLP3 in dysalphalipoproteidemia are associated with a difference in the triglyceride level of the blood plasma.

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What this paper is about

There has been determined the phospholipid composition in HDLP2 and HDLP3 obtained from the blood plasma of males with different cholesterol (CS) level of HDLP. An increase in CS of HDLP is shown to be associated with the increase in a percentage of phosphatidylcholine, a proportion of phosphatidylcholine/sphingomyelin and a reduction of the percentage of sphingomyelin (mainly in HDLP2) and to a lesser extent--in HDLP3. A direct correlation has been established between the level of CS of HDLP obtained from the blood plasma of males living in 3 different geographical zones of the USSR and the indices of the phospholipid composition of HDLP2. Changes found in the phospholipid composition of HDLP3 in dysalphalipoproteidemia are associated with a difference in the triglyceride level of the blood plasma.

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Available abstract

There has been determined the phospholipid composition in HDLP2 and HDLP3 obtained from the blood plasma of males with different cholesterol (CS) level of HDLP. An increase in CS of HDLP is shown to be associated with the increase in a percentage of phosphatidylcholine, a proportion of phosphatidylcholine/sphingomyelin and a reduction of the percentage of sphingomyelin (mainly in HDLP2) and to a lesser extent--in HDLP3. A direct correlation has been established between the level of CS of HDLP obtained from the blood plasma of males living in 3 different geographical zones of the USSR and the indices of the phospholipid composition of HDLP2. Changes found in the phospholipid composition of HDLP3 in dysalphalipoproteidemia are associated with a difference in the triglyceride level of the blood plasma.

Key concepts: Sphingomyelin, Phospholipid, Phosphatidylcholine, Composition (language), Triglyceride, Chemistry, Cholesterol, Internal medicine

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[Phospholipid characteristics of the HDLP2 and HDLP3 composition in dysalphalipoproteinemia]. — Research Paper | ScholarLens