2003•PubMedRequires access

[Effect of zinc on reproductive toxicity in rats].

Qing Wei, Rui-Quan Fan, Xingfen Yang, Tiejiang Chen

Abstract

The purpose of this study was to explore the effect of zinc on reproductive function in rats. The results revealed that the sperm count, sperm motility and reproductive function appeared to be enhanced in male rats by 60 days successive administration of low dose zinc (12 mg/kg) or medium dose zinc (120 mg/kg), whereas reproductive system damages characterized by lowering of reproductive function would be resulted by high dose zinc(240 mg/kg). However, no effect on the growth and development of the second generation was shown, suggesting that the injury was just limited to certain extent.

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Available abstract

Key concepts: Zinc, Sperm, Reproductive toxicity, Sperm motility, Toxicity, Andrology, Reproductive system, Reproduction