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HTLV-1: A Significant Retrovirus.

Randy D. Gascoyne

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Abstract

HTLV-1, or human T-lymphotropic virus type 1, is a retrovirus causing disease in humans. Responsible for adult T-cell leukemia/lymphoma, it is the first documented viral-induced neoplasia in humans. This same virus has recently been implicated in a progressive neurological disorder, and because it is transmissible by blood transfusion, it represents a major problem in blood banking. The relationship of this virus to other newly discovered retroviruses is discussed.

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What this paper is about

HTLV-1, or human T-lymphotropic virus type 1, is a retrovirus causing disease in humans. Responsible for adult T-cell leukemia/lymphoma, it is the first documented viral-induced neoplasia in humans. This same virus has recently been implicated in a progressive neurological disorder, and because it is transmissible by blood transfusion, it represents a major problem in blood banking. The relationship of this virus to other newly discovered retroviruses is discussed.

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Available abstract

HTLV-1, or human T-lymphotropic virus type 1, is a retrovirus causing disease in humans. Responsible for adult T-cell leukemia/lymphoma, it is the first documented viral-induced neoplasia in humans. This same virus has recently been implicated in a progressive neurological disorder, and because it is transmissible by blood transfusion, it represents a major problem in blood banking. The relationship of this virus to other newly discovered retroviruses is discussed.

Key concepts: Retrovirus, Virology, Virus, Deltaretrovirus, Human T-lymphotropic virus 1, Human T-lymphotropic virus, Disease, Leukemia

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