MODERN VIEWS ON GASTROESOPHAGEAL REFLUX DISEASE IN CHILDREN: ISSUES OF CLASSIFICATION, ETIOLOGY AND PATHOGENESIS (PART I)
Н. Н. Ахпаров, R.Z. Boranbaeva, S.B. Suleimanova, Lyazat Manzhuova
Abstract
Н. Н. Ахпаров, R.Z. Boranbaeva, S.B. Suleimanova, Lyazat Manzhuova
Abstract
The review is devoted to modern views on the etiology, pathogenesis, clinical picture, methods of diagnosis and surgical treatment of gastroesophageal reflux disease (GERD) in children. An analysis of scientific literature by domestic and foreign authors on the evolution of molecular genetic and cytogenetic studies, the role of morphological and immunohistochemical mechanisms in diagnostics is presented, the researchers’ opinions regarding the timing and tactics of surgical intervention, as well as the advantages of minimally invasive surgery for GERD are considered.
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The review is devoted to modern views on the etiology, pathogenesis, clinical picture, methods of diagnosis and surgical treatment of gastroesophageal reflux disease (GERD) in children. An analysis of scientific literature by domestic and foreign authors on the evolution of molecular genetic and cytogenetic studies, the role of morphological and immunohistochemical mechanisms in diagnostics is presented, the researchers’ opinions regarding the timing and tactics of surgical intervention, as well as the advantages of minimally invasive surgery for GERD are considered.
Key concepts: Etiology, GERD, Disease, Medicine, Reflux, Pathogenesis, Intervention (counseling), Intensive care medicine