2021Nepal Medical JournalOpen access

High-Grade Chondrosarcoma of Mandibular Molar Region- A Case Report and Review of Literature

Mala Kamboj, Anjali Narwal, Nisha Marwah, Ambika Gupta, Anju Devi, Akhil Girdhar

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Abstract

Chondrosarcomas are malignant tumors of cartilaginous origin with only 5-10% reported in the head and neck region. Intraorally it has higher incidence of occurrence in anterior maxilla followed by posterior mandible. The 5-year survival and metastases rates are adversely affected by the grade of tumor, which necessitates its early diagnosis. Histopathology and immunohistochemistry are vital for its accurate diagnosis. Chondrosarcomas being radio-and chemoresistant are treated surgically although adjuvant radiotherapy helps in prevention of local recurrences. A case of high-grade chondrosarcoma of the mandibular molar region is presented, along with pertinent review of literature.

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What this paper is about

Chondrosarcomas are malignant tumors of cartilaginous origin with only 5-10% reported in the head and neck region. Intraorally it has higher incidence of occurrence in anterior maxilla followed by posterior mandible. The 5-year survival and metastases rates are adversely affected by the grade of tumor, which necessitates its early diagnosis. Histopathology and immunohistochemistry are vital for its accurate diagnosis. Chondrosarcomas being radio-and chemoresistant are treated surgically although adjuvant radiotherapy helps in prevention of local recurrences. A case of high-grade chondrosarcoma of the mandibular molar region is presented, along with pertinent review of literature.

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Available abstract

Chondrosarcomas are malignant tumors of cartilaginous origin with only 5-10% reported in the head and neck region. Intraorally it has higher incidence of occurrence in anterior maxilla followed by posterior mandible. The 5-year survival and metastases rates are adversely affected by the grade of tumor, which necessitates its early diagnosis. Histopathology and immunohistochemistry are vital for its accurate diagnosis. Chondrosarcomas being radio-and chemoresistant are treated surgically although adjuvant radiotherapy helps in prevention of local recurrences. A case of high-grade chondrosarcoma of the mandibular molar region is presented, along with pertinent review of literature.

Key concepts: Cirrhosis, Ascites, Esophageal varices, Gastroenterology, Internal medicine, Portal hypertension, Albumin, Medicine

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