1998Journal of the European Academy of Dermatology and VenereologyRequires access

Disseminated papular acantholytic dyskeratosis

Magdalena Ciupinska

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Abstract

We present two cases of elderly women with clinically atypical transient disseminated papular eruption, showing suprabasal epidermal clefts with dyskeratosis and acantholysis. The clinical picture did not correspond to either Darier's disease, Hailey's disease or Graver's acantholysis. In spite of clinical similarity the cases differed in course and outcome. Overlapping dyskeratosis and acantholysis varied in different specimens. The case with transient acantholytic lesions of short duration showed much more pronounced dyskeratosis than the other in which several relapses occurred in a 4-year period. Such cases defying classification belong to the heterogeneous group of papular acantholytic dyskeratosis. (c) 1998 Elsevier Science B.V. All rights reserved

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We present two cases of elderly women with clinically atypical transient disseminated papular eruption, showing suprabasal epidermal clefts with dyskeratosis and acantholysis. The clinical picture did not correspond to either Darier's disease, Hailey's disease or Graver's acantholysis. In spite of clinical similarity the cases differed in course and outcome. Overlapping dyskeratosis and acantholysis varied in different specimens. The case with transient acantholytic lesions of short duration showed much more pronounced dyskeratosis than the other in which several relapses occurred in a 4-year period. Such cases defying classification belong to the heterogeneous group of papular acantholytic dyskeratosis. (c) 1998 Elsevier Science B.V. All rights reserved

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Available abstract

We present two cases of elderly women with clinically atypical transient disseminated papular eruption, showing suprabasal epidermal clefts with dyskeratosis and acantholysis. The clinical picture did not correspond to either Darier's disease, Hailey's disease or Graver's acantholysis. In spite of clinical similarity the cases differed in course and outcome. Overlapping dyskeratosis and acantholysis varied in different specimens. The case with transient acantholytic lesions of short duration showed much more pronounced dyskeratosis than the other in which several relapses occurred in a 4-year period. Such cases defying classification belong to the heterogeneous group of papular acantholytic dyskeratosis. (c) 1998 Elsevier Science B.V. All rights reserved

Key concepts: Acantholysis, Dyskeratosis, Medicine, Dermatology, Dyskeratosis congenita, Hyperkeratosis, Pathology, Immunology

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