1997Kazan medical journalRequires access

On treatment of moderate and severe forms of Flexner's dysentery 2a

A. G. Rakhmonova, В. А. Неверов, V. F. Tsinzeoling, N. I. Romanenkova, Kulikov Vp, Yu. V. Vasin, E. Yu. Goltsova, В. Х. Фазылов

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Abstract

The comparison of the treatment efficiency of patients with Flexner's 2a dysentery with fluochinolones (in peroral and parenteral administration) and antibacterial drugs of other groups is performed. The antibiotic sensitivity of Flexner 2a Shigella strains evolved from patients with midgrave and grave forms of dysentery (during life and postmortelly) using the methods of disks and serial cultivation is studied. It is established that the largest sensitivity of Flexner 2a Shigella is expressed in tarivid that is a highly effective antibacterial drug for the treatment of patients with midgrave and grave course of Flexner's dysentery. There is significant resistance of Flexner 2a Shigella to the traditionally used antibacterial drugs for the treatment of dysentery.

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What this paper is about

The comparison of the treatment efficiency of patients with Flexner's 2a dysentery with fluochinolones (in peroral and parenteral administration) and antibacterial drugs of other groups is performed. The antibiotic sensitivity of Flexner 2a Shigella strains evolved from patients with midgrave and grave forms of dysentery (during life and postmortelly) using the methods of disks and serial cultivation is studied. It is established that the largest sensitivity of Flexner 2a Shigella is expressed in tarivid that is a highly effective antibacterial drug for the treatment of patients with midgrave and grave course of Flexner's dysentery. There is significant resistance of Flexner 2a Shigella to the traditionally used antibacterial drugs for the treatment of dysentery.

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Available abstract

The comparison of the treatment efficiency of patients with Flexner's 2a dysentery with fluochinolones (in peroral and parenteral administration) and antibacterial drugs of other groups is performed. The antibiotic sensitivity of Flexner 2a Shigella strains evolved from patients with midgrave and grave forms of dysentery (during life and postmortelly) using the methods of disks and serial cultivation is studied. It is established that the largest sensitivity of Flexner 2a Shigella is expressed in tarivid that is a highly effective antibacterial drug for the treatment of patients with midgrave and grave course of Flexner's dysentery. There is significant resistance of Flexner 2a Shigella to the traditionally used antibacterial drugs for the treatment of dysentery.

Key concepts: Dysentery, Shigella, Antibiotics, Medicine, Bacillary dysentery, Drug resistance, Shigellosis, Shigella dysenteriae

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