2021•Journal of the Belgian Society of RadiologyOpen access

MRI of Wallerian Degeneration in the Brainstem: A Pictorial Essay

Nico Hustings, Marc M. Lemmerling

Abstract

Wallerian degeneration of the cerebral peduncle is a common MRI finding after cerebral injury. The degree of peduncular atrophy reflects the extent of damage in the corticospinal tract. The acute phase of Wallerian degeneration is visible with Diffusion-Weighted-Imaging. New investigation with Diffusion-Tensor-Imaging quantifies Wallerian degeneration in the subacute ischemic phase and is a good predictor for later functional recovery after stroke.

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Key concepts: Wallerian degeneration, Cerebral peduncle, Medicine, Corticospinal tract, Diffusion MRI, Degeneration (medical), Brainstem, Pyramidal tracts