2021•AntibioticsOpen access

Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies

Jean Gibb, Darren W. Wong

Abstract

is an urgent global threat due to its increasing incidence and intrinsic antibiotic resistance. Antibiotic development has focused on carbapenem-resistant Enterobacteriaceae, Pseudomonas, and Acinetobacter, with approved antibiotics in recent years having limited activity for Stenotrophomonas. Accordingly, novel treatment strategies for Stenotrophomonas are desperately needed. We conducted a systemic literature review and offer recommendations based on current evidence for a treatment strategy of Stenotrophomonas infection.

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Key concepts: Stenotrophomonas maltophilia, Stenotrophomonas, Antibiotics, Medicine, Antimicrobial, Antibiotic resistance, Intensive care medicine, Microbiology