TYPE 2 DIABETICS

Objective: To find the relationship between the serum cholesterol andtriglyceroid in type 2 diabetics with different parameters of obesity. Design: Descriptive study. Setting: Al-ShifaMetabolic Center Faisalabad. Period: From January 2003 to June 2005. Material and methods: A total of 2034patients, who fulfill the inclusion criteria were included in this study. Out of these patients 1188 females and 846 males,patients presented to the metabolic center for lipids screening. Body parameters i.e. weight, height, waist and hipcircumference and blood pressure. BMI and WHR were calculated as per standard. Fasting serum cholesterol andtriglyceroid were tested on capillary blood by GCT meter. Results: There is a sharp and definite increase in the % ofpatients having > 200 mg/dl total cholesterol after 10 years of DM, from 34-36% to 59%. More patients in above 50 agegroup had higher than 200-mg/dl-cholesterol i.e.38%, 50% and 36% than below 50 years i.e. 30% and 24%. Serumtriglyceroid levels in the middle range of 150-300 had a definite ascending relationship with increasing BMI, 17%, 47%and 71% respectively. High WHR in both sexes had the strongest relation with high serum cholesterol both in 150-200and >200 mg/dl range, 37% and 41% and 40 and 41% respectively. Serum triglyceroid was definitely higher in patientswith high WHR in both sexes in 150-300 ranges. Conclusions: It is clearly evident that the duration of hyperglycemia,age at onset of DM and the central obesity, all increases the chances of having hypercholesteremia. It is again evidentthat so many other factors influence the incidence of hypercholesteremia; screening is the only way to pick thesepatients. Every patient with any component of the Metabolic Syndrome must be screened for other components foroptimal stratification of the coronary risk factors.