2021•Acta Medica PhilippinaOpen access

Spot the Difference: A Case of Hailey-Hailey Disease in a 64-year-old Filipino Female

Raisa Celine R. Rosete, Juan Paolo David S. Villena, Mae N. Ramirez‐Quizon

Abstract

Hailey-Hailey disease (HHD) is an uncommon acantholytic disorder of the skin. This is a case of a 64-year-old Filipino female with a chronic history of painful and malodorous intertriginous plaques. Histopathologic evaluation showed overlapping features of pemphigus vulgaris and Hailey-Hailey disease. A negative direct immunofluorescence test clinched the diagnosis of Hailey-Hailey disease. The patient was advised regarding preventive measures and treated with topical antibiotics and corticosteroids with improvement of her lesions.

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Available abstract

Key concepts: Hailey–Hailey disease, Intertriginous, Medicine, Dermatology, Pemphigus vulgaris, Disease, Pemphigus, Family history