2021•Canadian Medical Association JournalOpen access

Innovations in cancer immunotherapy: chimeric antigen receptor T-cell therapy (CAR-T)

Kevin Brown, Matthew D. Seftel, Kevin Anthony Hay

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Abstract

KEY POINTS Cellular immunotherapy is a novel therapy where the body’s own immune cells are harnessed for their anticancer effect. One of the most exciting of these approaches is chimeric antigen receptor T-cell therapy (CAR-T). This therapy is now standard of care for relapsed or refractory B-cell

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KEY POINTS Cellular immunotherapy is a novel therapy where the body’s own immune cells are harnessed for their anticancer effect. One of the most exciting of these approaches is chimeric antigen receptor T-cell therapy (CAR-T). This therapy is now standard of care for relapsed or refractory B-cell

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Available abstract

KEY POINTS Cellular immunotherapy is a novel therapy where the body’s own immune cells are harnessed for their anticancer effect. One of the most exciting of these approaches is chimeric antigen receptor T-cell therapy (CAR-T). This therapy is now standard of care for relapsed or refractory B-cell

Key concepts: Chimeric antigen receptor, Immunotherapy, Cell therapy, Medicine, Cancer immunotherapy, Immunology, Antigen, T cell

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