Evaluation of Keto-Test in Urine and Milk for the Detection of Subclinical Ketosis in Periparturient Holstein Dairy Cattle
Tera M. Osborne, K.E. Leslie, T.F. Duffield, Christina S. Petersson, J. Ten Hag, Yoshihiro Okada
Abstract
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Tera M. Osborne, K.E. Leslie, T.F. Duffield, Christina S. Petersson, J. Ten Hag, Yoshihiro Okada
Abstract
Open-access reader
Subclinical ketosis causes significant economic loss to producer by decreasing milk production and increasing risk of periparturient disease. The dairy industry needs a cowside test to monitor periparturient dairy cattle for subclinical ketosis. The objective of this study was to determine the sensitivity, specificity and predictive values of the semi-qualitative Keto-Test in periparturient dairy cattle. This test was previously evaluated (Geishauser et al, J Dairy Sci, 2000) and shown to have a sensitivity and specificity of 80% and 76%, respectively, using a cut-point of 100 μmol/L betahydroxybutyrate (BHBA) or greater as a positive. However, in that evaluation tests were not performed prior to parturition or in the immediate periparturient period.
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Subclinical ketosis causes significant economic loss to producer by decreasing milk production and increasing risk of periparturient disease. The dairy industry needs a cowside test to monitor periparturient dairy cattle for subclinical ketosis. The objective of this study was to determine the sensitivity, specificity and predictive values of the semi-qualitative Keto-Test in periparturient dairy cattle. This test was previously evaluated (Geishauser et al, J Dairy Sci, 2000) and shown to have a sensitivity and specificity of 80% and 76%, respectively, using a cut-point of 100 μmol/L betahydroxybutyrate (BHBA) or greater as a positive. However, in that evaluation tests were not performed prior to parturition or in the immediate periparturient period.
Key concepts: Ketosis, Subclinical infection, Dairy cattle, Urine, Animal science, Milk production, Dairy industry, Medicine