2021•Molecular Biology ReportsRequires access

Ursodeoxycholic acid shows antineoplastic effects in bile duct cancer cells via apoptosis induction; p53 activation; and EGFR-ERK, COX-2, and PI3K-AKT pathway inhibition

Jin Lee, Eun Mi Hong, Jung Han Kim, Jung Hee Kim, Jang Han Jung, Se Woo Park, Dong Hee Koh, Hyun Joo Jang

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Key concepts: Ursodeoxycholic acid, Protein kinase B, Cancer research, Bile duct cancer, Apoptosis, Cancer cell, PI3K/AKT/mTOR pathway, MAPK/ERK pathway

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Ursodeoxycholic acid shows antineoplastic effects in bile duct cancer cells via apoptosis induction; p53 activation; and EGFR-ERK, COX-2, and PI3K-AKT pathway inhibition — Research Paper | ScholarLens