Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot study

Introduction Follicular and serum vitamin D are considered potential markers of the oocyte and embryos' quality and predictors of IVF outcomes. Material and methods This retrospective cross-sectional study correlated vitamin D in sera and follicular fluid of women with unexplained infertility mutually and with IVF outcomes. ELISA was used for measuring Vitamin D. Results Results show only a positive correlation between follicular and serum levels of Vitamin D (Rho=0.615, p=0.025) and between follicular levels of Vitamin D with the percentage of embryo fragmentation (Rho=0.544; p=0.036). Conclusions Results suggests that serum and follicular fluid vitamin D measurements could be complementary tools to the routine assessment of embryos.