2021eNeurologicalSciOpen access

IgG4-related hypothalamo-hypophysitis

Yuki Urushida, Daisuke Ishikawa, Mayuri Yanaizumi, Takumi Nakamura, Masakuni Amari, Takeshi Kawarabayashi, Masahiko Tosaka, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji

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Abstract

•A patient exhibited IgG4-related hypothalamo-hypophysitis.•Prominent high-signal areas of swelling were observed in the hypothalamus, tuber cinereum, infundibulum, and bilateral optic nerve systems.•MRI T1WI with contrast media demonstrated enhanced neurohypophysis and cystic swelling, and compressed anterior pituitary.•MRI findings improved rapidly after 4 days of steroid therapy.

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What this paper is about

•A patient exhibited IgG4-related hypothalamo-hypophysitis.•Prominent high-signal areas of swelling were observed in the hypothalamus, tuber cinereum, infundibulum, and bilateral optic nerve systems.•MRI T1WI with contrast media demonstrated enhanced neurohypophysis and cystic swelling, and compressed anterior pituitary.•MRI findings improved rapidly after 4 days of steroid therapy.

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Available abstract

•A patient exhibited IgG4-related hypothalamo-hypophysitis.•Prominent high-signal areas of swelling were observed in the hypothalamus, tuber cinereum, infundibulum, and bilateral optic nerve systems.•MRI T1WI with contrast media demonstrated enhanced neurohypophysis and cystic swelling, and compressed anterior pituitary.•MRI findings improved rapidly after 4 days of steroid therapy.

Key concepts: Infundibulum, Hypophysitis, Medicine, Hypothalamus, Swelling, Magnetic resonance imaging, Pituitary stalk, Pituitary gland

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