2021•Bioorganic & Medicinal ChemistryOpen access

Synthesis and duplex-forming ability of oligonucleotides modified with 4′-C,5′-C-methylene-bridged nucleic acid (4′,5′-BNA)

Takao Yamaguchi, Chika Yamamoto, Masahiko Horiba, Hiroshi Aoyama, Satoshi Obika

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Key concepts: Chemistry, Oligonucleotide, Nucleic acid, Duplex (building), Thymine, Nucleobase, DNA, Nucleic acid analogue

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Synthesis and duplex-forming ability of oligonucleotides modified with 4′-C,5′-C-methylene-bridged nucleic acid (4′,5′-BNA) — Research Paper | ScholarLens