A Antimicrobial Effects of Matrica® and Chlorehexidine Mouthwashes Compared with Sodium Hypochlorite on Enterococcus Faecalis and Candida Albicans: An In Vitro Study

Introduction: Bacteria and their products have an important role in root treatment failure and their continued presence in seemingly well-filled canals, cause disturbances in healing process after the treatment. Thus the use of proper disinfectants for mechanical cleaning of canals has a great importance. Nowadays, scientists are seeking better alternatives with greater efficiency and less toxic effect for common chemical disinfectants. Therefore, the aim of this study was to evaluate the antimicrobial effects of Matrica and Chlorhexidine compared to Sodium hypochlorite on Enterococcus faecalis and Candida albicans in the laboratory conditions. Materials & Methods: In this in vitro study, Candida albicans and Enterococcus faecalis microorganisms were cultured with Kirby Bauer method on Mueller Hinton agar medium. Then paper disks impregnated with Matrica (pure and 50), chlorhexidine (0.2 and 0.1) and sodium hypochlorite 1 were placed on the medium. Forty-eight hours later, the zone of growth inhibition was measured in terms of millimeters. Data were analyzed by SPSS-18 software using ANOVA and TUKEY statistical tests. Results: According to the findings of this study, the highest mean diameter of inhibition zone of bacteria Enterococcus faecalis and Candida albicans, was for sodium hypochlorite 1 followed by chlorhexidine 0.2, chlorhexidine 0.1, pure Matrica and Matrica 50, respectively (P<0.000). Conclusion: Considering the results of this study, it seems that the antimicrobial effect of herbal composition of Matrica is not as efficient as sodium hypochlorite and chlorhexidine.