2021Al-Azhar International Medical Journal /Al-Azhar International Medical JournalOpen access

Labetalol versus Alpha Methyldopa for Control of Pregnancy Induced Hypertension

Shokry El-sadek, Ahmed Mohammed El-Sadek, Abdalla Ahmed

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Abstract

Background: Hypertension is a common medical problematic faced throughout pregnancy and is accompanied with raised risks of opposing consequences, Objective: This work aimed to match the effectiveness of labetolol and alpha methyldopa in blood pressure (BP) control in women with Pregnancy Induced Hypertension (PIH). Methods: This observational study was performed at Department of Obstetrics and Gynecology of AL- HUSSIEN University Hospital and Suez General Hospital after obtaining an approval from institutional board review of Al Azhar University Faculty of Medicine. Results: A significant change among the studied group in regard to mean drop in SBP and DBP, and Period needed to control BP in labetalol group was significantly lower compared to α-Methyldopa group, Conclusion: Hypertensive diseases throughout gestation are a main reason of morbidity and death all over the world. Antihypertensive drugs have a significant function in treating maternal BP. The current work approves the preceding results that labetalol is an operative and secure medication for usage faster in accomplishing acceptable in controlling of BP in PIH, in our work we found that Labetalol controls systolic and diastolic Bp more quickly and efficiently than Methyldopa.

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Background: Hypertension is a common medical problematic faced throughout pregnancy and is accompanied with raised risks of opposing consequences, Objective: This work aimed to match the effectiveness of labetolol and alpha methyldopa in blood pressure (BP) control in women with Pregnancy Induced Hypertension (PIH). Methods: This observational study was performed at Department of Obstetrics and Gynecology of AL- HUSSIEN University Hospital and Suez General Hospital after obtaining an approval from institutional board review of Al Azhar University Faculty of Medicine. Results: A significant change among the studied group in regard to mean drop in SBP and DBP, and Period needed to control BP in labetalol group was significantly lower compared to α-Methyldopa group, Conclusion: Hypertensive diseases throughout gestation are a main reason of morbidity and death all over the world. Antihypertensive drugs have a significant function in treating maternal BP. The current work approves the preceding results that labetalol is an operative and secure medication for usage faster in accomplishing acceptable in controlling of BP in PIH, in our work we found that Labetalol controls systolic and diastolic Bp more quickly and efficiently than Methyldopa.

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Available abstract

Background: Hypertension is a common medical problematic faced throughout pregnancy and is accompanied with raised risks of opposing consequences, Objective: This work aimed to match the effectiveness of labetolol and alpha methyldopa in blood pressure (BP) control in women with Pregnancy Induced Hypertension (PIH). Methods: This observational study was performed at Department of Obstetrics and Gynecology of AL- HUSSIEN University Hospital and Suez General Hospital after obtaining an approval from institutional board review of Al Azhar University Faculty of Medicine. Results: A significant change among the studied group in regard to mean drop in SBP and DBP, and Period needed to control BP in labetalol group was significantly lower compared to α-Methyldopa group, Conclusion: Hypertensive diseases throughout gestation are a main reason of morbidity and death all over the world. Antihypertensive drugs have a significant function in treating maternal BP. The current work approves the preceding results that labetalol is an operative and secure medication for usage faster in accomplishing acceptable in controlling of BP in PIH, in our work we found that Labetalol controls systolic and diastolic Bp more quickly and efficiently than Methyldopa.

Key concepts: Labetalol, Methyldopa, Medicine, Blood pressure, Pregnancy, Hypertension in Pregnancy, Observational study, Drugs in pregnancy

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