2017JOURNAL OF PEDIATRIC CRITICAL CAREOpen access

Recurrent guillain-barre syndrome in a pediatric patient - Residual opthalmoplegia that recovered with IV immunoglobulins A case report

Sandeep Kadam, GSandeep Kumar, Manasa Kakunje

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Abstract

Guillain-Barré syndrome(GBS) is the most common and most severe acute paralytic neuropathy, with about 1,00,000 people developing the disorder every year worldwide. Under the umbrella term of Guillain-Barré syndrome are several recognisable variants with distinct clinical and pathological features. GBS is generally considered to be mono- phasic, but recurrences do occur in a presently undefined subgroup of patients. Recurrent GBS is rare but presents a diagnostic challenge. Even though not well described, reccurences have been reported, though there appears to be no significant difference between RGBS and GBS episodes with respect to similar clinical symptoms and similar or different triggering events. We describe a 10-year-old girl who presented with acute onset of ascending, symmetrical, areflexic, flaccid quadriparesis. She had a history of GBS 1 year ago from which she recovered completely over 6 months with no residual weakness except for ophthalmoplegia. Based on clinical presentation, past history and investigations, diagnosis of recurrent GBS was confirmed.

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What this paper is about

Guillain-Barré syndrome(GBS) is the most common and most severe acute paralytic neuropathy, with about 1,00,000 people developing the disorder every year worldwide. Under the umbrella term of Guillain-Barré syndrome are several recognisable variants with distinct clinical and pathological features. GBS is generally considered to be mono- phasic, but recurrences do occur in a presently undefined subgroup of patients. Recurrent GBS is rare but presents a diagnostic challenge. Even though not well described, reccurences have been reported, though there appears to be no significant difference between RGBS and GBS episodes with respect to similar clinical symptoms and similar or different triggering events. We describe a 10-year-old girl who presented with acute onset of ascending, symmetrical, areflexic, flaccid quadriparesis. She had a history of GBS 1 year ago from which she recovered completely over 6 months with no residual weakness except for ophthalmoplegia. Based on clinical presentation, past history and investigations, diagnosis of recurrent GBS was confirmed.

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Available abstract

Guillain-Barré syndrome(GBS) is the most common and most severe acute paralytic neuropathy, with about 1,00,000 people developing the disorder every year worldwide. Under the umbrella term of Guillain-Barré syndrome are several recognisable variants with distinct clinical and pathological features. GBS is generally considered to be mono- phasic, but recurrences do occur in a presently undefined subgroup of patients. Recurrent GBS is rare but presents a diagnostic challenge. Even though not well described, reccurences have been reported, though there appears to be no significant difference between RGBS and GBS episodes with respect to similar clinical symptoms and similar or different triggering events. We describe a 10-year-old girl who presented with acute onset of ascending, symmetrical, areflexic, flaccid quadriparesis. She had a history of GBS 1 year ago from which she recovered completely over 6 months with no residual weakness except for ophthalmoplegia. Based on clinical presentation, past history and investigations, diagnosis of recurrent GBS was confirmed.

Key concepts: Guillain-Barre syndrome, Medicine, Pediatrics, Weakness, Pathological, Natural history, Presentation (obstetrics), Disease

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