Comparison of the effects of volume-controlled ventilation and pressure-controlled ventilation modes on hemodynamics, respiratory mechanics and blood gas parameters in patients undergoing laparoscopic cholecystectomy

Background: This study aimed to compare the changes induced by VCV and PCV modes in hemodynamics, respiration (airway pressures, gas exchange parameters) and metabolism (acid-base balance) in patients undergoing laparoscopic cholecystectomy.Methods: Patients were divided into two randomised groups as volume-controlled ventilation (VCV) group (VC) and pressure-controlled ventilation (PCV) group (PC). The following parameters were recorded at 3 different time points: T1: in supine position 10 minutes after induction of anaesthesia, T2: 15 minutes after CO2 insufflation in inverted Trendelenburg position (head 30 degrees up), T3: 10 minutes after CO2 desufflation. HR, SpO2, SAP (systolic arterial pressure), DAP (diastolic arterial pressure), MAP (mean arterial pressure), PetCO2 (end-tidal carbon dioxide pressure), Ppeak, Pplateau, Pmean, Vt (tidal volume) and compliance with the available data, the cases in both groups Vd, Vd/Vt ratios and P(A-a)O2 were calculated. Arterial blood gas parameters (pH, PaO2, PaCO2, SaO2, P(a-et)CO2) values were recorded.Results: It was found that Ppeak and Pplateau values were significantly higher in the VC group (p<0.05). It was found that compliance was significantly higher in the PC group (p<0.05) (p<0.01). In the postoperative period, it was found that PaO2 values were significantly higher in the PC group compared to the VC group (p<0.05). It was found that the P(A-a)O2 values of the PC group were significantly higher than those of the VC group during the desufflation phase (p<0.05).Conclusions: We think that PCV mode can be a good alternative for the prevention and correction of physiopathological changes due to laparoscopic surgery.