2021•European Journal of PharmacologyOpen access

Pharmacological and molecular docking studies reveal that glibenclamide competitively inhibits diazoxide-induced mitochondrial ATP-sensitive potassium channel activation and pharmacological preconditioning

Plínio Bezerra Palácio, Aline Maria Brito Lucas, Joana Varlla de Lacerda Alexandre, Pedro Lourenzo Oliveira Cunha, Yuana Ivia Ponte Viana, Amanda Cabral Albuquerque, Anna Lídia Nunes Varela, Heberty Tarso Facundo

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Key concepts: Diazoxide, Glibenclamide, Cardioprotection, Sulfonylurea receptor, Potassium channel, Pharmacology, ATP-sensitive potassium channel, Potassium channel opener