Assessment of Efficacy and Safety Profile of Platelet Rich Plasma (PRP) Therapy with Dermaroller in the Treatment of Female Pattern Hair Loss

INTRODUCTION: Female pattern hair loss is the most common type of hair loss affecting women. Prevalence of FPHL is not well known as there is no universally accepted criteria for the disease. FPHL presents with hair thinning with 3 different patterns- Ludwig/Sinclair, Olsen & Hamilton. The visible thinning in FPHL results from follicular miniaturization. AIM OF THE STUDY: To find an effective alternative treatment modality for patients with female pattern hair loss of childbearing age. OBJECTIVE: To assess the efficacy and safety of Platelet Rich Plasma (PRP) therapy with Derma roller in the treatment of Female Pattern Hair Loss (FPHL). METHODOLOGY: In this study, 40 patients diagnosed as female pattern hair loss attending Dermatology outpatient department, who fulfilled the inclusion criteria were included. The patients were explained about the procedure, post-operative follow up and possible adverse effects. Four sittings of PRP with Derma roller was done at 1-month interval. Photos taken and grade improvement was noted. Final grading and images were taken at 2 months post treatment. RESULTS: About 87% of patients had improvement in the grade of hair loss after 6 months with better improvement seen after 3 sessions of treatment. The mean quality of life of the patients improved from 11 to 8 i.e.; from very large effect on patient’s life to moderate effect on patient’s life after 6 months. CONCLUSION: In this study, majority of the patients showed hair re-growth with decrease in hair fall and few patients showed decrease in hair fall despite having no improvement in hair loss. Majority of the patients did not experience any adverse effect. Thus, platelet rich plasma therapy with derma roller can be considered as an option in the treatment of female pattern hair loss with a good safety profile.