Risk factors associated with canine parvovirus disease in dogs: A case-control study

Canine parvovirus type-2 (CPV-2) is one of the most contagious viral agents causing acute enteritis in pups with high rate of morbidity and mortality. The study aimed to investigate the risk factors associated with canine parvovirus (CPV) occurrence in dogs in Ho Chi Minh City, Vietnam. A total number of 132 dogs less than six months of age were recruited in the study and split into two groups: ‘CPV diseased dogs’ included 44 (33.3%) dogs positive with canine parvovirus confirmed by rapid immune-migration test, and ‘normal dogs’ consisted of 88 (66.7%) healthy dogs. Results indicated that the unvaccinated dogs had 11.76 times more risk of CPV infection than vaccinated dogs (OR = 11.76,P<0.001). The risk of CPV in dogs raised with others at the same age was 5.01 times (OR = 5.01,P= 0.027) higher than those raised singly. The risk of CPV infection of dogs interacting with neighbour dogs was 3.13 times (OR = 3.13,P= 0.028) higher than the dogs having no contact with other dogs living nearby. Briefly, our study highlights potential factors for CPV disease prevention, especially CPV vaccination is the most important driver affecting the occurrence of parvovirus in young dogs