ScholarLens Back to search
2021•Journal of Research in Medical and Dental ScienceOpen access

A Comparative Study of Quantitative Buffy Coat (QBC) and Rapid Diagnostic Test (RDT) Against the Conventional Peripheral Blood Smear Microscopy in the Early Detection and Diagnosis of Malaria in Children

C Selvendran, S Jagadeeswari, S Sundari

Open full text 0 citations

Abstract

The Present study includes a comparative study evaluating the diagnostic value of Quantitative Buffy Coat and Rapid Diagnostic Test (using pLDH) against the conventional peripheral blood smear microscopy, in the diagnosis of malaria in children between 6 months to 14 years of age. The present study focuses on the clinical profile of malaria cases detected by the peripheral smear. RDT (pLDH) is highly sensitive in picking up falciparum cases, which is equivalent to QBC. So, it can be used as a diagnostic tool for falciparum malaria where facilities of expert microscopy/ QBC are not available. The sensitivity of RDT (pLDH) in diagnosing vivax malaria is lower than that of peripheral smear microscopy and QBC.

About this research paper

What this paper is about

The Present study includes a comparative study evaluating the diagnostic value of Quantitative Buffy Coat and Rapid Diagnostic Test (using pLDH) against the conventional peripheral blood smear microscopy, in the diagnosis of malaria in children between 6 months to 14 years of age. The present study focuses on the clinical profile of malaria cases detected by the peripheral smear. RDT (pLDH) is highly sensitive in picking up falciparum cases, which is equivalent to QBC. So, it can be used as a diagnostic tool for falciparum malaria where facilities of expert microscopy/ QBC are not available. The sensitivity of RDT (pLDH) in diagnosing vivax malaria is lower than that of peripheral smear microscopy and QBC.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

The Present study includes a comparative study evaluating the diagnostic value of Quantitative Buffy Coat and Rapid Diagnostic Test (using pLDH) against the conventional peripheral blood smear microscopy, in the diagnosis of malaria in children between 6 months to 14 years of age. The present study focuses on the clinical profile of malaria cases detected by the peripheral smear. RDT (pLDH) is highly sensitive in picking up falciparum cases, which is equivalent to QBC. So, it can be used as a diagnostic tool for falciparum malaria where facilities of expert microscopy/ QBC are not available. The sensitivity of RDT (pLDH) in diagnosing vivax malaria is lower than that of peripheral smear microscopy and QBC.

Key concepts: Buffy coat, Diagnosis of malaria, Malaria, Peripheral blood, Plasmodium vivax, Medicine, Plasmodium falciparum, Diagnostic test

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
A Comparative Study of Quantitative Buffy Coat (QBC) and Rapid Diagnostic Test (RDT) Against the Conventional Peripheral Blood Smear Microscopy in the Early Detection and Diagnosis of Malaria in Children — Research Paper | ScholarLens