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2021•Progress of Digestive EndoscopyOpen access

A case of cecal granular cell tumor resected by endoscopic submucosal dissection (ESD)

Mana Yamamoto, Yutaka Mitsunaga, Takayuki Okamura, Yorinari Ochiai, Junnosuke Hayasaka, Yugo Suzuki, Nobuhiro Dan, Masami Tanaka, Kosuke Nomura, Hiroyuki Odagiri, Satoshi Yamashita, Akira Matsui, Mana Ideyama, Yutaka Takazawa, Daisuke Kikuchi, Shu Hoteya

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Abstract

A 60-year-old woman underwent lower gastrointestinal endoscopy and a yellowish submucosal tumor of 5 mm in size was found on the contralateral side of the ileocecal valve. The tumor was diagnosed as a granular cell tumor by endoscopic ultrasonography (EUS) and biopsy examination. ESD was carefully conducted after injection of glycerol. On pathological examination, a tumor consisting of round cells filled with eosinophilic granular spores was found in the submucosa. The spores were strongly positive for S100 protein.

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What this paper is about

A 60-year-old woman underwent lower gastrointestinal endoscopy and a yellowish submucosal tumor of 5 mm in size was found on the contralateral side of the ileocecal valve. The tumor was diagnosed as a granular cell tumor by endoscopic ultrasonography (EUS) and biopsy examination. ESD was carefully conducted after injection of glycerol. On pathological examination, a tumor consisting of round cells filled with eosinophilic granular spores was found in the submucosa. The spores were strongly positive for S100 protein.

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Available abstract

A 60-year-old woman underwent lower gastrointestinal endoscopy and a yellowish submucosal tumor of 5 mm in size was found on the contralateral side of the ileocecal valve. The tumor was diagnosed as a granular cell tumor by endoscopic ultrasonography (EUS) and biopsy examination. ESD was carefully conducted after injection of glycerol. On pathological examination, a tumor consisting of round cells filled with eosinophilic granular spores was found in the submucosa. The spores were strongly positive for S100 protein.

Key concepts: Granular cell tumor, Submucosa, Medicine, Endoscopic submucosal dissection, Endoscopic ultrasound, Endoscopic mucosal resection, Biopsy, Endoscopy

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