From Surviving Sepsis to Surviving Sepsis-Associated Acute Kidney Injury: Focusing on Risk Stratification of Acute Kidney Injury / Acute Kidney Disease After Sepsis

Acute kidney injury (AKI) and chronic kidney disease (CKD), including end-stage kidney disease, enjoy primacy in the lexicon of nephrologists. Murkier is acute kidney disease (AKD) and the related concept of kidney recovery.1 The causal loop of AKI and CKD—that AKI increases risk for CKD, and CKD increases risk for AKI—is well appreciated in nephrology. AKD captures the “in-between” limb of this loop connecting AKI to CKD. For this reason, we are well served to understand how AKI patients may be risk stratified with respect to their risk of progression to new CKD (or progression of existing CKD).