A Novel Herbal Topical Formulation for Wound Healing

Wound healing is dynamic and complex process which requires suitable surrounding to promote healing. Routine wound healing management is tedious and time consuming to promote wound healing. Crocculus hirsutus is used traditionally as anti-inflammatory, antimicrobial and antioxidant.The extract is having gelling and film forming property. This can be utilized for making medicated films for the therapy of wound healing activity. But there is no scientific evidences to prove these activities with the help of preclinical in-vivo screening. There is no marketed dosage form of the selected extract. Hence the objective of the present study is to formulate the topical film for management of wound. Methodology: The ethanolic extract of leaves was pharmacologically evaluated and showed significant anti-inflammatory, antioxidant and antimicrobial activity. The films were prepared by incorporating inert excipients in ethanolic extract and wound healing activity was evaluated in experimental animals by excision method. It is observed that the excision wound was significantly recovered with the help of formulated film.