Yong Ruan, Houqiang Xu, Xinqin Ji, Jiafu Zhao
Abstract
observations. Our results demonstrated that the expression of P53 is affected by the binding of BLM and EZH2 to the MDM2 promoter region. This finding indicated that EZH2 regulates the expression of MDM2 at the transcriptional level by interacting with BLM.
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observations. Our results demonstrated that the expression of P53 is affected by the binding of BLM and EZH2 to the MDM2 promoter region. This finding indicated that EZH2 regulates the expression of MDM2 at the transcriptional level by interacting with BLM.
Key concepts: Gene knockdown, EZH2, Cancer research, Prostate cancer, Mdm2, In vivo, Biology, Cancer