2021•International Journal of Medical AnesthesiologyOpen access

A comparative study of side effects of intravenous etomidate (0.3mg/Kg) versus propofol (2mg/Kg) during induction of anaesthesia and endotracheal intubation

Shoji Koshy, Jithin J Cherian

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Abstract

Patients given propofol should be constantly monitored and facilities for maintenance of a patient airway, artificial ventilation, oxygen enrichment and other resuscitative facilities should be readily available at all times. Apnoea often occurs during induction and may persist for more than 60 seconds. Group 1 patient following premedication receives injection Propofol 2mg/kg i.v. and group 2 patient following premedication receives inj. Etomidate 0.3mg/kg i.v. for induction of anaesthesia. Required parameters in haemodynamics and side effects were compared with the help of proforma data analysis. the mean value of Ramsey sedation scale for etomidate group was 2.1 ± 0.58 whereas it was 2.18 ± 0.75 for propofol group. There was no statistical significance between both groups on inter-group analysis.

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Patients given propofol should be constantly monitored and facilities for maintenance of a patient airway, artificial ventilation, oxygen enrichment and other resuscitative facilities should be readily available at all times. Apnoea often occurs during induction and may persist for more than 60 seconds. Group 1 patient following premedication receives injection Propofol 2mg/kg i.v. and group 2 patient following premedication receives inj. Etomidate 0.3mg/kg i.v. for induction of anaesthesia. Required parameters in haemodynamics and side effects were compared with the help of proforma data analysis. the mean value of Ramsey sedation scale for etomidate group was 2.1 ± 0.58 whereas it was 2.18 ± 0.75 for propofol group. There was no statistical significance between both groups on inter-group analysis.

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Available abstract

Patients given propofol should be constantly monitored and facilities for maintenance of a patient airway, artificial ventilation, oxygen enrichment and other resuscitative facilities should be readily available at all times. Apnoea often occurs during induction and may persist for more than 60 seconds. Group 1 patient following premedication receives injection Propofol 2mg/kg i.v. and group 2 patient following premedication receives inj. Etomidate 0.3mg/kg i.v. for induction of anaesthesia. Required parameters in haemodynamics and side effects were compared with the help of proforma data analysis. the mean value of Ramsey sedation scale for etomidate group was 2.1 ± 0.58 whereas it was 2.18 ± 0.75 for propofol group. There was no statistical significance between both groups on inter-group analysis.

Key concepts: Etomidate, Premedication, Propofol, Anesthesia, Medicine, Sedation, Intubation, Endotracheal intubation

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A comparative study of side effects of intravenous etomidate (0.3mg/Kg) versus propofol (2mg/Kg) during induction of anaesthesia and endotracheal intubation — Research Paper | ScholarLens