Pure Red Cell Aplasia and Autoimmune Hemolytic Anemia in Chronic Lymphocytic Leukemia; Case Report and Literature Review
Shafquat Khan, Muhammad Ifham Hanif, Umair Ahmed, Musa Azhar, Samia Yasmeen, Neelam Siddiqui
Abstract
Shafquat Khan, Muhammad Ifham Hanif, Umair Ahmed, Musa Azhar, Samia Yasmeen, Neelam Siddiqui
Abstract
This paper outlines the case report of Chronic Lymphocytic Leukemia (CLL) presenting with two immune dysregulation phenomena, Autoimmune Hemolytic Anemia (AIHA) and Pure Red Cell Aplasia (PRCA) in the same patient. CLL, despite an immune deficient state, harbors autoimmunity presenting in the form of cytopenias. Autoimmune cytopenias are associated with poor prognosis and warrant different therapeutic approach.
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This paper outlines the case report of Chronic Lymphocytic Leukemia (CLL) presenting with two immune dysregulation phenomena, Autoimmune Hemolytic Anemia (AIHA) and Pure Red Cell Aplasia (PRCA) in the same patient. CLL, despite an immune deficient state, harbors autoimmunity presenting in the form of cytopenias. Autoimmune cytopenias are associated with poor prognosis and warrant different therapeutic approach.
Key concepts: Pure red cell aplasia, Autoimmune hemolytic anemia, Chronic lymphocytic leukemia, Medicine, Aplasia, Immunology, Leukemia, Anemia