2020•International Journal of Medical Reviews and Case ReportsOpen access

Pure Red Cell Aplasia and Autoimmune Hemolytic Anemia in Chronic Lymphocytic Leukemia; Case Report and Literature Review

Shafquat Khan, Muhammad Ifham Hanif, Umair Ahmed, Musa Azhar, Samia Yasmeen, Neelam Siddiqui

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Abstract

This paper outlines the case report of Chronic Lymphocytic Leukemia (CLL) presenting with two immune dysregulation phenomena, Autoimmune Hemolytic Anemia (AIHA) and Pure Red Cell Aplasia (PRCA) in the same patient. CLL, despite an immune deficient state, harbors autoimmunity presenting in the form of cytopenias. Autoimmune cytopenias are associated with poor prognosis and warrant different therapeutic approach.

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What this paper is about

This paper outlines the case report of Chronic Lymphocytic Leukemia (CLL) presenting with two immune dysregulation phenomena, Autoimmune Hemolytic Anemia (AIHA) and Pure Red Cell Aplasia (PRCA) in the same patient. CLL, despite an immune deficient state, harbors autoimmunity presenting in the form of cytopenias. Autoimmune cytopenias are associated with poor prognosis and warrant different therapeutic approach.

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Available abstract

This paper outlines the case report of Chronic Lymphocytic Leukemia (CLL) presenting with two immune dysregulation phenomena, Autoimmune Hemolytic Anemia (AIHA) and Pure Red Cell Aplasia (PRCA) in the same patient. CLL, despite an immune deficient state, harbors autoimmunity presenting in the form of cytopenias. Autoimmune cytopenias are associated with poor prognosis and warrant different therapeutic approach.

Key concepts: Pure red cell aplasia, Autoimmune hemolytic anemia, Chronic lymphocytic leukemia, Medicine, Aplasia, Immunology, Leukemia, Anemia

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