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2021•Open Forum Infectious DiseasesOpen access

Clinical Effectiveness of Lyme Vaccine: A Matched Case–Control Study

Carlos R. Oliveira, Christopher Massad, Eugene D. Shapiro, Marietta Vázquez

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Abstract

We conducted a matched case-control study to assess the effectiveness of Lyme vaccine (LYMErix) as it was used in clinical practice. We found ≥3 doses to be 71% effective against Lyme disease. This is the first study to show that the Lyme vaccine is effective in a real-world setting.

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What this paper is about

We conducted a matched case-control study to assess the effectiveness of Lyme vaccine (LYMErix) as it was used in clinical practice. We found ≥3 doses to be 71% effective against Lyme disease. This is the first study to show that the Lyme vaccine is effective in a real-world setting.

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OpenAlex reports 7 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

We conducted a matched case-control study to assess the effectiveness of Lyme vaccine (LYMErix) as it was used in clinical practice. We found ≥3 doses to be 71% effective against Lyme disease. This is the first study to show that the Lyme vaccine is effective in a real-world setting.

Key concepts: Lyme disease, Medicine, LYME, Immunology, Virology, Borrelia burgdorferi, Antibody

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