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PHARMACO - ANALYTICAL AND EXPERIMENTAL STUDY OF DARVYAADI GHRITA WITH SPECIAL REFERENCE TO WOUND HEALING EFFECT Haldar

Pronab, Mishra, Mahapatra

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Abstract

Ayurveda has propagated many excellent remedies for Vrana ropan (wound healing). Darvyaadi ghrita is one among them. Gada Nigraha mentions it, as the best for Ropana (healing). Healing or closure of a wound has many associated complications like infection, scarring etc. An effort has been made for evaluation of wound healing property of Dravyadi ghrita through animal experimental study. Wound healing property of Darvyaadi ghrita was evaluated through excision wound model and incision wound model on albino rats. 24 albino rats were selected and grouped into 4 of 6 animals in each group. In excision wound, percentage contraction of the wound and period of epithelialization was studied. In incision wound, tensile strength or breaking strength of the wound was studied. Study showed that Darvyaadi ghrita possess superior wound healing properties than the control group. Statistically, Darvyaadi ghrita showed significantly results on all assessed parameters.

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What this paper is about

Ayurveda has propagated many excellent remedies for Vrana ropan (wound healing). Darvyaadi ghrita is one among them. Gada Nigraha mentions it, as the best for Ropana (healing). Healing or closure of a wound has many associated complications like infection, scarring etc. An effort has been made for evaluation of wound healing property of Dravyadi ghrita through animal experimental study. Wound healing property of Darvyaadi ghrita was evaluated through excision wound model and incision wound model on albino rats. 24 albino rats were selected and grouped into 4 of 6 animals in each group. In excision wound, percentage contraction of the wound and period of epithelialization was studied. In incision wound, tensile strength or breaking strength of the wound was studied. Study showed that Darvyaadi ghrita possess superior wound healing properties than the control group. Statistically, Darvyaadi ghrita showed significantly results on all assessed parameters.

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Available abstract

Ayurveda has propagated many excellent remedies for Vrana ropan (wound healing). Darvyaadi ghrita is one among them. Gada Nigraha mentions it, as the best for Ropana (healing). Healing or closure of a wound has many associated complications like infection, scarring etc. An effort has been made for evaluation of wound healing property of Dravyadi ghrita through animal experimental study. Wound healing property of Darvyaadi ghrita was evaluated through excision wound model and incision wound model on albino rats. 24 albino rats were selected and grouped into 4 of 6 animals in each group. In excision wound, percentage contraction of the wound and period of epithelialization was studied. In incision wound, tensile strength or breaking strength of the wound was studied. Study showed that Darvyaadi ghrita possess superior wound healing properties than the control group. Statistically, Darvyaadi ghrita showed significantly results on all assessed parameters.

Key concepts: Wound healing, Wound closure, Medicine, Breaking strength, Surgery, Composite material, Materials science

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