2001•Acta Scientiarum Naturalium Universitatis SunyatseniRequires access
Establishment of transgenic mouse harboring hepatitis B virus (adr subtype) genomes
Yi Yi, Ping Ping, Hû, Wei Wei, Jiang, Wen Wen, Chao, Zheng, Jian JIAN, Xiu Xiu, Li, Shun, Dai, Xin, Min, Wang, Shu, Zhong, Zhang, Hồng, Yu Y, Sun, Guang, Rong Rong, Hao
Abstract
INTRODUCTIONHepatitis B virus (HBV) belongs to the group ofhepatovirus, a major pathogen of human acute andchronic hepatitis B[1 4], which has a very closeassociation with human hepatocellular carcinoma(HCC)[5-8], For example, a statistical data from ahospital in Shanghai showed that 80% of HCCpatients were positive for HBsAg ( personalcommunication).