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2021•Journal of NeurophysiologyOpen access

Estimates of persistent inward currents increase with the level of voluntary drive in low-threshold motor units of plantar flexor muscles

Lucas B. R. Orssatto, Karen Mackay, Anthony Shield, Raphael Luiz Sakugawa, Anthony J. Blazevich, Gabriel S. Trajano

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Abstract

Animal experiments and computational models have shown that motor neurons can amplify the synaptic input they receive via persistent inward currents. Here we show in humans that this amplification varies proportionally to the magnitude of the voluntary drive to the muscle.

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Animal experiments and computational models have shown that motor neurons can amplify the synaptic input they receive via persistent inward currents. Here we show in humans that this amplification varies proportionally to the magnitude of the voluntary drive to the muscle.

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Available abstract

Animal experiments and computational models have shown that motor neurons can amplify the synaptic input they receive via persistent inward currents. Here we show in humans that this amplification varies proportionally to the magnitude of the voluntary drive to the muscle.

Key concepts: Plantar flexion, Isometric exercise, Motor unit, Vastus medialis, Chemistry, Turnover, Motor unit recruitment, Electromyography

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Estimates of persistent inward currents increase with the level of voluntary drive in low-threshold motor units of plantar flexor muscles — Research Paper | ScholarLens