Comparison of enhancement features of peripheral intrahepatic cholangiocarcinoma on contrast-enhanced ultrasound and dynamic enhanced CT

Objective To analyze and compare features of peripheral intrahepatic cholangiocarcinoma(ICC)in CEUS and dynamic enhanced CT.Methods Thirty patients with ICC(36lesions)confirmed by pathology were analyzed retrospectively,and the CEUS characteristics were compared with those of dynamic CT.Results Thirty-six lesions manifested hyper-enhancement in arterial phase and displayed hypoecho in the portal and delayed phase on CEUS.All lesions displayed fast-in and fast-outenchancement pattern.On dynamic CT,all lesions present the same characteristics as CEUS in the arterial phase,28lesions showed hyper-enhancement continuously,and the rest hypo-enhanced in the portal and delayed phase.On CEUS,19lesions(19/36,52.78%)displayed rim-like enhancement,17(17/36,47.22%)displayed gross enhancement.During the process of enhancement,the pattern of branch-like from peripheral to inside was observed in 21lesions(21/36,58.33%).On dynamic CT,22lesions(22/36,61.11%)showed rim-like enhancement,5of them describing separate enhancement and 14(14/36,38.89%)showed gross enhancement.At the peak intensity,23lesions were inhomogeneous and 13were homogeneous on CEUS,whereas 20were inhomogeneous and 16were homogeneous on dynamic CT.The accuracy of CEUS was 70.00%(21/30)according to the standard offast-in and fast-out,rim-like and/or branch-like enhancement during the arterial phase.The accuracy of dynamic CT was 73.33%(22/30)according torimlike enhancementin the arterial phase and hyper-enhancement continuously.The diagnostic accuracy of these two methods appeared good consistency(Kappavalue is 0.824).Conclusion ICC has some characteristics in CEUS and dynamic CT,both of them have high diagnostic value.