Comparative Study of Individual Pain relief Effect of Intravenous Ibuprofen Intravenous Morphine, Intravenous ketorolac Separately in renal colic Patient ED

Background and objectives: Renal colic can be managed by preventing the contraction movements of ureter muscles. By reducing prostogelandin nonsteroidal anti-inflammatory drugs could be used as an effective analgesics drugs in renal colic. The aim of this study is to investigate the comparison of Ibuprofen, Ketorolac and morphin on acute renal colic pain relief. Materials and methods: The present study was a double-blind clinical trial in which the patients suffering from acute renal colic were randomly divided into 3 groups of who either received intravenous infusion of 30 mg of Ketorolac, IV Ibuprofen or morphine. Severity of patients’ pain was measured by visual analogue scale (VAS) at baseline, ,30,60 and 120 minutes after infusion. The collected data were analyzed using SPSS statistical software. Results: The three groups were similar in baseline pain score and demographic characteristics. At different time points, mean pain show statistically significant differences between the groups; patients received ibuprofen showed the least VAS. Conclusion: The results of this study showed that Ibuprofen can be superior to ketorolac and morphine in treatment of patients suffering from renal colic