Assessing Proteinuria in Chronic Kidney Disease: Protein- Creatinine Ratio Vs Albumin-Creatinine Ratio
Meenakshi Ganesh, Divya Dharshini B
Abstract
Meenakshi Ganesh, Divya Dharshini B
Abstract
Quantification of proteinuria is important in the assessment of chronic kidney disease (CKD).Early detection and treatment for CKD can reduce the progression of kidney disease and its complications like cardiovascular disease. The aim of this study was to find out a better parameter to identify proteinuria(albuminuria) in CKD patients. The study design is a case control study with 50 controls (apparently healthy) with normal urine protein to creatinine ratio (uPCR→0.0-0.3) and normal eGFR and 50 chronic kidney disease(CKD) patients as cases with increased uPCR and decreased eGFR (GFR 0.005 and is not significant.Urine albumin to creatinine ratio(uACR) was found to be superior than urine protein to creatinine ratio(uPCR) to identify proteinuria mainly albuminuria in CKD patients.
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Quantification of proteinuria is important in the assessment of chronic kidney disease (CKD).Early detection and treatment for CKD can reduce the progression of kidney disease and its complications like cardiovascular disease. The aim of this study was to find out a better parameter to identify proteinuria(albuminuria) in CKD patients. The study design is a case control study with 50 controls (apparently healthy) with normal urine protein to creatinine ratio (uPCR→0.0-0.3) and normal eGFR and 50 chronic kidney disease(CKD) patients as cases with increased uPCR and decreased eGFR (GFR 0.005 and is not significant.Urine albumin to creatinine ratio(uACR) was found to be superior than urine protein to creatinine ratio(uPCR) to identify proteinuria mainly albuminuria in CKD patients.
Key concepts: Proteinuria, Albuminuria, Creatinine, Kidney disease, Medicine, Urology, Renal function, Internal medicine