Transdermal Drug Delivery Systems

Transdermal drug delivery has developed significance in the field medicine, but it has to develop its potential in order to use it as an alternative to oral route of drug delivery and intravenous injections. The First-generation transdermal delivery systems have been used for delivery of small, lipophilic, low-dose drugs. Second-generation delivery systems are used for chemical enhancers, non-cavitational ultrasound and iontophoresis. Third-generation delivery systems, thermal ablation can be used as a penetration enhancer. Micro needles and thermal ablation are widely used through clinical trials for delivery of vaccines and macromolecules. Using these novel second- and third-generation features, transdermal delivery has increased its significance in the current medical field.