2001•Acta Scientiarum Naturalium Universitatis SunyatseniRequires access

Effects of glycyrrhetinic acid on collagen metabolism of hepatic stellate cells at different stages of liver fibrosis in rats

Ji, YAO YAO, Wang, Qi, Sheng, Chang Zhang, Guo, Mei Mei, Yu, Hu

Abstract

INTRODUCTIONLiver fibrosis is a dynamic course leading tocirrhosis from a various chronic liver diseases. Thepathological basis of fibrosis is the disturbance ofproduction and degradation of the extracellularmatrix (ECM), which causes accumulation of ECMin the liver[1,2].

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Key concepts: Hepatic stellate cell, Fibrosis, Hepatic fibrosis, Liver fibrosis, Metabolism, Medicine, Pathology, Chemistry