2009Chinese Journal of Natural MedicinesRequires access

Triterpenes from the Fruits of Phellodendron chinense Schneid var. glabriusculum Schneid

Hao Xiao

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Abstract

AIM: To investigate the chemical constituents from the fruits of Phellodendron chinense Schneid var. glabriusculum Schneid. METHODS: The constituents of ethyl acetate-soluble portions in the 95% ethanol extract were iso-lated and purified by various chromatographic methods. Their structures were identified by their physicochemical characteris-tics and spectral data. RESULTS: Eight known compounds were isolated and identified as piscidinol A(1), phellochin(2), niloticin (3), dihydroniloticin (4), 21, 23-epoxy-21α, 24, 25-trihydroxytirucalla-7-en-3-one (5), 2α, 25-dimethylmeliano-diol-[(21R, 23R)-epoxy-24-hydroxy-21α, 25-methoxy]tirucalla-7-en-3-one (6), boujotinolone A (7), 3-ketooleanane(8). CONCLUSION: Compounds 5~8 are isolated from Phellodendron chinense Schneid var. glabriusculum Schneid. for the first time.

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AIM: To investigate the chemical constituents from the fruits of Phellodendron chinense Schneid var. glabriusculum Schneid. METHODS: The constituents of ethyl acetate-soluble portions in the 95% ethanol extract were iso-lated and purified by various chromatographic methods. Their structures were identified by their physicochemical characteris-tics and spectral data. RESULTS: Eight known compounds were isolated and identified as piscidinol A(1), phellochin(2), niloticin (3), dihydroniloticin (4), 21, 23-epoxy-21α, 24, 25-trihydroxytirucalla-7-en-3-one (5), 2α, 25-dimethylmeliano-diol-[(21R, 23R)-epoxy-24-hydroxy-21α, 25-methoxy]tirucalla-7-en-3-one (6), boujotinolone A (7), 3-ketooleanane(8). CONCLUSION: Compounds 5~8 are isolated from Phellodendron chinense Schneid var. glabriusculum Schneid. for the first time.

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Available abstract

AIM: To investigate the chemical constituents from the fruits of Phellodendron chinense Schneid var. glabriusculum Schneid. METHODS: The constituents of ethyl acetate-soluble portions in the 95% ethanol extract were iso-lated and purified by various chromatographic methods. Their structures were identified by their physicochemical characteris-tics and spectral data. RESULTS: Eight known compounds were isolated and identified as piscidinol A(1), phellochin(2), niloticin (3), dihydroniloticin (4), 21, 23-epoxy-21α, 24, 25-trihydroxytirucalla-7-en-3-one (5), 2α, 25-dimethylmeliano-diol-[(21R, 23R)-epoxy-24-hydroxy-21α, 25-methoxy]tirucalla-7-en-3-one (6), boujotinolone A (7), 3-ketooleanane(8). CONCLUSION: Compounds 5~8 are isolated from Phellodendron chinense Schneid var. glabriusculum Schneid. for the first time.

Key concepts: Chemical constituents, Traditional medicine, Terpene, Botany, Chemistry, Ethyl acetate, Biology, Chromatography

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