2007中国药理学报:英文版Requires access

Minocycline inhibits 5-1ipoxygenase activation and brain inflammation after focal cerebral ischemia in rats

Li-sheng, Michael Jen Jie Chu, San-Hua, Fang, Yu, Zhou, Guoliang, Meng-ling, Wang, Weiping, Xiangjian Zhang, Er-qing, Wei Nie

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Abstract

目的:决定 minocycline onpostis化学家大脑损害的反煽动性的效果是否被 5-lipoxygenase (5哈鱼)的抑制调停在 rats.Methods 的表示 andenzymatic 激活:焦点的服的局部缺血与 middlecerebral 动脉吸藏为 30 min 被导致,由 reperfusion.The ischemic 损害列在后面,内长的 IgG 渗出, neutrophils 和 macrophage/microglia 的 theaccumulation ,和5哈鱼 mRNA 表示被决定 72 hafter reperfusion.5哈鱼代谢物( leukotriene

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目的:决定 minocycline onpostis化学家大脑损害的反煽动性的效果是否被 5-lipoxygenase (5哈鱼)的抑制调停在 rats.Methods 的表示 andenzymatic 激活:焦点的服的局部缺血与 middlecerebral 动脉吸藏为 30 min 被导致,由 reperfusion.The ischemic 损害列在后面,内长的 IgG 渗出, neutrophils 和 macrophage/microglia 的 theaccumulation ,和5哈鱼 mRNA 表示被决定 72 hafter reperfusion.5哈鱼代谢物( leukotriene

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Available abstract

目的:决定 minocycline onpostis化学家大脑损害的反煽动性的效果是否被 5-lipoxygenase (5哈鱼)的抑制调停在 rats.Methods 的表示 andenzymatic 激活:焦点的服的局部缺血与 middlecerebral 动脉吸藏为 30 min 被导致,由 reperfusion.The ischemic 损害列在后面,内长的 IgG 渗出, neutrophils 和 macrophage/microglia 的 theaccumulation ,和5哈鱼 mRNA 表示被决定 72 hafter reperfusion.5哈鱼代谢物( leukotriene

Key concepts: Minocycline, Microglia, Ischemia, Inflammation, Leukotriene B4, Macrophage, Medicine, Leukotriene

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Minocycline inhibits 5-1ipoxygenase activation and brain inflammation after focal cerebral ischemia in rats — Research Paper | ScholarLens