2015•中国药理学报：英文版Requires access

Modulation of the pentose phosphate pathway alters phase I metabolism of testosterone and dextromethorphan in HepG2 cells

Wenjing, Xiao Xiao, Adeline Su Yien Ting, M. A, ○ Chun, Ge Ge, Wenjuan, Xia, Yong, Mao Mao, Run-bin,  Sun, Xiaoyi, Yu, Jiye, Aa, Guang-ji, Wang

Open publisher page 0 citations

Abstract

目的: 戊糖磷酸盐小径(PPP ) 涉及 glucose-6-phosphate 脱氢酶(G6PD ) 和 NADPH 的产生的活动，它在药新陈代谢起一个关键作用。这研究的目的是在 vitro 在药新陈代谢能力上调查 PPP 的调整的效果。

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Dextromethorphan, Pentose phosphate pathway, Metabolism, Chemistry, Modulation (music), Endocrinology, Testosterone (patch), Phase (matter)