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2021•Bioorganic & Medicinal Chemistry LettersOpen access

Structure–activity relationship studies of 3-substituted pyrazoles as novel allosteric inhibitors of MALT1 protease

Ken Nunettsu Asaba, Yohei Adachi, Kazuyuki Tokumaru, Akira Watanabe, Yasufumi Goto, Takumi Aoki

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Key concepts: Chemistry, Allosteric regulation, Structure–activity relationship, Enzyme inhibitor, IC50, Stereochemistry, Caspase, Enzyme

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